Slay the Spire 2 — Strategy Guides
In-depth guides covering characters, builds, tier lists, and game mechanics. Written by experienced players.
Character Guides
Direct entry points for the five searchable character guide pages.
Ironclad Guide
Builds, cards, relics, and boss plans for Ironclad.
Silent Guide
Poison, Sly, and combo routes for Silent.
Defect Guide
Focus, orbs, and scaling plans for Defect.
Regent Guide
Star management and forge sequencing for Regent.
Necrobinder Guide
Doom thresholds, Osty management, and soul engines.
Event Guides
Event hub plus detailed choice-by-choice routes.
Enemy Guides
Boss-first encounter guides plus the full enemy database hub.
All Enemies Guide
Study major fights by act, danger, and counterplay.
Slime Boss Guide
Split timing, cleanup windows, and common mistakes.
The Guardian Guide
Defensive Mode timing and phase management.
Hexaghost Guide
Turn-one planning, burn clutter, and setup windows.
Beginner Guides
Core learning content for first clears and early Ascension progress.
Beginner Tips and Tricks
Core principles for drafting, pathing, and surviving the early game.
All Characters Overview
Use this before picking your first main character.
Combat Mechanics Deep Dive
Block, intent, debuffs, and advanced sequencing fundamentals.