Top-player reference

Slay the Spire 2 Relic Tier List

This page turns the reference ranking into a cleaner relic-by-relic view. Names and effects stay aligned with the site database, while each info tooltip summarizes the main reason a relic rises or falls.

Hover the question-mark icon on any relic for a short note about why it ranks there.

How to Read This Page

The ranking is adapted from the DownS relic discussion you provided, then cross-checked against the current Mobalytics relic tier list to fill obvious coverage gaps. It is still summarized into short practical notes rather than copied verbatim.

S Tier

Run-defining relics with premium consistency, immediate safety, or scaling that asks almost nothing from the deck.

9 items
Anchor

Anchor

S Tier
Effect

Start each combat with 10 Block.

Bag of Preparation

Bag of Preparation

S Tier
Effect

At the start of each combat, draw 2 additional cards.

Gambling Chip

Gambling Chip

S Tier
Effect

At the start of each combat, discard any number of cards then draw that many.

Toxic Egg

Toxic Egg

S Tier
Effect

Whenever you add a Skill into your Deck, Upgrade it.

Razor Tooth

Razor Tooth

S Tier
Effect

Every time you play an Attack or Skill, Upgrade it for the remainder of combat.

Membership Card

Membership Card

S Tier
Effect

50% discount on all products!

Ringing Triangle

Ringing Triangle

S Tier
Effect

Retain your Hand on the first turn of combat.

Gorget

Gorget

S Tier
Effect

At the start of each combat, gain 4 Plating.

Ice Cream

Ice Cream

S Tier
Effect

Energy is now conserved between turns.

A Tier

Excellent relics that are strong in most runs, but need a little more context or are slightly less warping than S tier.

14 items
Amethyst Aubergine

Amethyst Aubergine

A Tier
Effect

Enemies drop 15 additional Gold.

Festive Popper

Festive Popper

A Tier
Effect

At the start of each combat, deal 9 damage to ALL enemies.

Happy Flower

Happy Flower

A Tier
Effect

Every 3 turns, gain 1 Energy.

Lantern

Lantern

A Tier
Effect

Start each combat with an additional Energy.

Meal Ticket

Meal Ticket

A Tier
Effect

Whenever you enter a shop room, heal 15 HP.

Blood Vial

Blood Vial

A Tier
Effect

At the start of each combat, heal 2 HP.

Lunar Pastry

Lunar Pastry

A Tier
Effect

At the end of your turn, gain 1 Star.

Orange Dough

Orange Dough

A Tier
Effect

At the start of each combat, add 2 random Colorless cards into your Hand.

Red Mask

Red Mask

A Tier
Effect

At the start of each combat, apply 1 Weak to ALL enemies.

Toolbox

Toolbox

A Tier
Effect

At the start of each combat, choose 1 of 3 random Colorless cards and add the chosen card into your Hand.

Vajra

Vajra

A Tier
Effect

Start each combat with 1 Strength.

Venerable Tea Set

Venerable Tea Set

A Tier
Effect

Whenever you enter a Rest Site, start the next combat with an additional Energy.

War Paint

War Paint

A Tier
Effect

Upon pickup, Upgrade 2 random Skills.

Whetstone

Whetstone

A Tier
Effect

Upon pickup, Upgrade 2 random Attacks.

B Tier

Good relics with clear upside, but they are either narrower, slower, or less efficient than the top groups.

13 items
Beating Remnant

Beating Remnant

B Tier
Effect

You cannot lose more than 20 HP in a single turn.

Bronze Scales

Bronze Scales

B Tier
Effect

Start each combat with 3 Thorns.

Centennial Puzzle

Centennial Puzzle

B Tier
Effect

The first time you lose HP each combat, draw 3 cards.

Dolly's Mirror

Dolly's Mirror

B Tier
Effect

Upon pickup, obtain an additional copy of a card in your Deck.

Frozen Egg

Frozen Egg

B Tier
Effect

Whenever you add a Power into your Deck, Upgrade it.

Ninja Scroll

Ninja Scroll

B Tier
Effect

At the start of each combat, add 3 Shivs into your Hand.

Oddly Smooth Stone

Oddly Smooth Stone

B Tier
Effect

Start each combat with 1 Dexterity.

Old Coin

Old Coin

B Tier
Effect

Upon pickup, gain 300 Gold.

Regal Pillow

Regal Pillow

B Tier
Effect

Whenever you Rest, heal an additional 15 HP.

Shuriken

Shuriken

B Tier
Effect

Every time you play 3 Attacks in a single turn, gain 1 Strength.

Strawberry

Strawberry

B Tier
Effect

Upon pickup, raise your Max HP by 7.

Tungsten Rod

Tungsten Rod

B Tier
Effect

Whenever you would lose HP, lose 1 less.

The Courier

The Courier

B Tier
Effect

The merchant no longer runs out of cards, relics, or potions and his prices are reduced by 20%.

C Tier

Situational or awkward picks that can work, but often miss the fights and floor states that matter most.

5 items
Tiny Mailbox

Tiny Mailbox

C Tier
Effect

Whenever you Rest, procure a random potion.

Juzu Bracelet

Juzu Bracelet

C Tier
Effect

Regular enemy combats are no longer encountered in ? rooms.

Potion Belt

Potion Belt

C Tier
Effect

Upon pickup, gain 2 potion slots.

Power Cell

Power Cell

C Tier
Effect

At the start of each combat, add 2 zero-cost cards from your Draw Pile into your Hand.

Brimstone

Brimstone

C Tier
Effect

At the start of your turn, gain 2 Strength and ALL enemies gain 1 Strength.

D Tier

Relics with major deck tax, unreliable payoff, or downside patterns that can actively lose runs.

4 items
Cauldron

Cauldron

D Tier
Effect

Upon pickup, brews 5 random potions.

Book of Five Rings

Book of Five Rings

D Tier
Effect

Every 5 cards you add to your Deck, heal 20 HP.

Dingy Rug

Dingy Rug

D Tier
Effect

Card rewards can now contain Colorless cards.

Dragon Fruit

Dragon Fruit

D Tier
Effect

Whenever you gain Gold, raise your Max HP by 1.